The Content Effectiveness in Red Ginger (Zingiber officinale Rosc.) Variety to Increase Immunity

  • Tabitha Sri Hartati Wulandari
  • Ainun Mirza Nurhaniefa
  • Windhiana Ayu Lestari
Keywords: red ginger, immune system, pandemic, Covid-19

Abstract

Coronavirus Disease 2019 (Covid-19) has become a very worrying disease outbreak in several countries, one of which is Indonesia. Covid-19 is an infectious disease caused by a newly discovered type of coronavirus and has been an epidemic since December 2019 in Wuhan, China. This coronavirus can cause respiratory tract infections in humans. Based on data analysis from the COVID19 Handling Committee and the National Economic Recovery, stated that confirmed cases of the corona virus in Indonesia as of April 9, 2021 reached 1,558,145 people, of which 1,405,659 people were declared cured and 42,348 people were declared dead (Covid19.go, 2021) . Cases infected with COVID-19 will continue to increase if people do not orderly comply with health protocols. In addition, it is necessary to increase the community's immune system so that it is not easily infected. The immune system is very important to be improved and maintained during the COVID19 pandemic. One of the efforts to improve the body's immune system is to take vitamin c supplements. However, during this pandemic, vitamin C supplement products are limited and prices have skyrocketed. So that other alternative materials are needed that are cheap, easy to obtain, and most importantly have a fairly high antioxidant content. One alternative material that can be used according to these criteria is red ginger (Zingiber officinale Rosc.). The purpose of this activity is to find out more about the effectiveness of red ginger as an alternative immune-boosting ingredient. This research was conducted by means of a literature study by reviewing articles related to the effectiveness of red ginger to increase immunity. The results obtained indicate that red ginger is effective in increasing the body's immunity because red ginger cointain vitamin A, vitamin E, vitamin C, selenium, iron and zinc. The plant is one of them red ginger (Zingiber officinale). The compounds in red ginger are reported to have properties as antibacterial, antioxidant, anti-inflammatory, analgesic, diuretic, antifungal, anticancer, and antiviral.

References

[1] Ahkam, A. H., Hermanto, F.E., Alamsyah A., Aliyyah I.H., and Fatchiyah F., 2020, Virtual prediction of antiviral potential of ginger (Zingiber officinale) bioac-tive compounds against spike and MPro of SARSCoV2. Journal of Biological Researches, Vol. 25, No. 2: 52–57.

[2] Anonymous (1997). Monographs on the medicinal uses of plants. Exeter: European Scientific Cooperative on Phytotherapy.

[3] Aryanta, I. W. R., 2019, Manfaat Jahe Untuk Kesehatan. E-Jurnal Widya Kesehatan,Volume 1, No. 2 : 39-40.

[4] Chen BH, Wu PY, Chen KM, Fu TF, Wang HM, Chen CY (2009). Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiberofficinale (Ginger) J. Nat. Prod. 72:950-953

[5] Das, M., Banerji, A., Cheemalapati, V.N. and Hazra, J., 2020. Antiviral Activity Of Indian Medicinal Plants: Prventive Measures For COVID-19. Journal of Global Biosciences, Vol.9, No.5 : 7307- 7319.

[6] Dewi, Y. K. and Riyandari, A. B. 2020. Potensi Tanaman Lokal sebagai Tanaman Obat dalam Menghambat Penyebaran COVID-19. Jurnal Pharmascience, Vol. 07, No.02, hal: 112-128.

[7] Dhanasekaran, S. and Pradeep P.S., 2020, Scope Of Phytotherapeutics In Targeting ACE2 Mediated Host-Viral Interface of SARS‐CoV2 That Causes COVID-19. Preprint: ChemRxiv.

[8] Ernst E, Pittler MH (2004). Randomized controlled trial of ginger to treat nausea and vomiting in pregnancy. Obstet. Gynecol. 103(4):639-645.

[9] Frisch C, Hasenohrl RU, Mattern CM, Hacker R, Huston JP (1995). Blockade of lithium chloride-induced conditioned place aversion as a test for antiemetic agents: comparison of metoclopramide with combined extracts of Zingiber officinale and Ginkgo biloba. Pharmacol. Biochem. Behav. 52:321-327.

[10] Gong QM, Wang SL, Gan C (1989). A clinical study on the treatment of acute upper digestive tract hemorrhage with wen-she decoction. Chung Hsi I Chieh Ho Tsa Chih 9:272-273, 260.

[11] Ha SK, Moon E, Ju MS, Kim DH, Ryu JH, Oh MS, Kim SY (2012). 6 Shogaol, a ginger product, modulates neuroinflammation: a new approach to neuroprotection. Neuropharmacology 63(2):211-23.

[12] Huang Q, Iwamoto M, Aoki S, Tanaka N, Tajima K, Yamahara J (1991). Anti-5 hydroxytryptamine effect of galanolactone, diterpenoid isolated from ginger. Chem. Pharm. Bull. 39:397-399.

[13] Kaushik, S., Jangra, G., Kundu, V., Yadav, J.P. and Kaushik, S., 2020, Antiviral Activity of Zingiber officinale (Ginger) Ingredients Against The Chikungunya Virus. Virus Disease, 2020 May, 5 : 1-7.

[14] Kementerian Kesehatan RI, 2021, Situasi Terkini Perkembangan Novel Coronavirus (COVID-19).
https://infeksiemerging.kemkes.go.id/dashboard/covid-19. Diakses 9 Januari 2021.

[15] Liao YR, Leu YL, Chan YY, KuoPC, Wu TS (2012). Anti-platelet aggregation and vasorelaxing effects of the constituents of the rhizomes of Zingiber officinale. Molecules 17(8):8928-8937.

[16] Nur, Y., Cahyoutomo, A., Nanda, N. and Fistoro, N., 2020, Profil GC-MS Senyawa Metabolit Sekunder dari Jahe Merah (Zingiber officinale) dengan Metode Ekstraksi Etil Asetat, Etanol dan Destilasi. Jurnal Sains dan Kesehatan, Vol.2, No.3 : 198- 204.

[17] Magzoub, M., 2020, Life Style Guideline of Ginger (Zingiber officinale) as Prophylaxis and Treatment for Coronaviruses (SARS-CoV-2) Infection (COVID-19). Saudi Journal of Biomedical Research, Vol 5, No. 6 : 125-127.

[18] Pecoraro A, Patel J, Guthrie T, Ndubisi B 1998. Efficacy of ginger as an adjunctive anti-emetic in acute chemotherapy-induced nausea and vomiting. ASHP Midyear Clinical Meeting.33:429.

[19] Qian DS, Liu ZS (1992). Pharmacologic studies of antimotion sickness actions of ginger. Chung Kuo Chung Hsi I Chieh Ho Tsa Chih 12:95-98.

[20] Rajapaksa, R.M.H., Perera, B.T., Nisansala, M.J., Perera, W.P.R.T. and Dissanayake, K.G.C., 2020, Potential Of Inhibiting The Receptor Binding Mechanism Of SARSCOV-2 Using Phytochemical Extracts Of Medicinal Herb; Moleculer Docking Study. Global Journal of Engineering Science and Research Management, Vol. 7, No.4 : 51-61.

[21] Siswanto, B. and Ernawati, F., 2013, Peran Beberapa Zat Gizi Mikro Dalam Sistem Imunitas. Gizi Indonesia, Vol.36, No.1 : 57-64.

[22] Syahrir, A., Rahem, A. and Prayoga, A., 2020, Religiositas Mahasiswa Farmasi UIN Malang Selama Pandemi COVID-19. Journal of Halal Product and Research, Vol.3, No.1 : 25-34.

[23] Ware, M. 2017. Ginger: Health Benefits and Dietary Tips. https://www.medicalnewstoday.com/articles/265990.php. (diakses tanggal 9 Januari 2021)

[24] World Health Organization, 2020. Coronavirus Disease (COVID-19): Situastion report-177. https://www.who.int/emergencies/diseases/novelcoronavirus2019/situationreports (diakses 9 Januari 2021).
Published
2021-07-30